We present the development of a new algorithm which combines state-of-the-art energy-dispersive x-ray (EDX) spectroscopy theory and a suitable machine learning formulation for the hyperspectral unmixing of scanning transmission electron microscope EDX spectrum images. The algorithm is based on non-negative matrix factorization (NMF) incorporating a physics-guided factorization model. ... https://www.jmannino.com/quick-offer-Nemacor-Maxx-4-for-Dogs-flash-choice/